Department of Biomolecular Electronics

Current national projects:

Projects of the National Research Foundation of Ukraine (NRFU):

  1. 2023-2025 – project “Creation of an enzymatic kit and portable biosensors for express analysis of creatinine – a marker of acute renal dysfunction” under competition “Science for Security and Sustainable Development” (supervisor – S.V. Dzyadevych )
  2. 2023-2024 – project No. 2022.01/0022 « Sensory platform based on graphene and textiles for metabolites analysis in sweat " under competition “Science for reconstruction Ukraine in war and post-war periods” (supervisor – Korpan Ya.I.)
  3. 2023-2024 – project No. 2022.01/0043 «Development of portable system for express monitoring of lactate/pyruvate correlation in the blood for urgent needs clinical diagnostics", under competition " Science for reconstruction Ukraine in war and post-war periods " (supervisor – Soldatkin O.O.)

Projects funded by the National Academy of Sciences of Ukraine:

Budget program "Support for the development of priority areas of scientific research" (KPKVK 6541230)

  1. "Development of technology for creating biosensor test systems for enzyme activity analysis as diagnostic indicator of internal organ damage" (2025–2026; supervisor – S.V. Dzyadevych)

Goal program of the NAS of Ukraine for fundamental research "Promising fundamental research and innovative developments of nanomaterials and nanotechnologies for the needs of the healthcare industry and agriculture" for 2020-2024.

    No. 54 Н - “Biofunctionalized semiconductor nanocrystals for the development of impediometric DNA sensors for early diagnosis of genetic diseases” (2020–2022; supervisor – O. P. Soldatkin)

Goal program scientific research of the NAS of Ukraine «Semiconductors materials, technologies and sensors for technical diagnostic, control and system management» for 2018-2020

  1. No. ТД12-2-2020 - Creation and implementation of experimental samples of portable biosensor analyzers for express determination of toxins (2018–2020; supervisor – S.V. Dzyadevych)

Comprehensive scientific and technical Program of the National Academy of Sciences of Ukraine "Smart" sensors appliances of new generation based on modern materials and technologies":

  1. No. 8/1 – Creation of sensor systems based on smartphones and " smart " biomimetic polymers for selective definition of food toxins and endocrine destroyers (2018–2022; supervisor – T.A. Sergeyeva)
  2. No. 9/2 - Development and optimization of biosensor systems for neurotransmitters monitoring for express diagnostics and neuropathologies treatment efficiency control. (2018–2022; supervisor – O.O. Soldatkin)
  3. No. 10 /2 - Development and optimization of enzymatic electrochemical biosensors based on new functional nanomaterials for the determination of arginine and their application for quality control of fruit and berry juices and hygiene products (2018–2022; supervisor – S.V. Dzyadevych)
  4. No. 12/1 - Development and optimization of a portable device based on enzymatic electrochemical biosensors for the analysis of mycotoxins in agricultural crops and products (2018–2022; supervisor – V.M. Arkhypova)
  5. No. 13/2 - Creation of smart sensor devices for the analysis of creatinine and ammonium ions based on new nanocomposite films (2018–2022; supervisor – Ya.I. Korpan)
  6. No. 14/2 - Development of a “smart” portable indicator of the solutions general toxicity based on an enzyme multibiosensor (2018–2022; supervisor – O.O. Soldatkin)
  7. No. 16/2 - Increasing the informativeness and metrological reliability of electrochemical enzyme biosensor systems based on modern materials (2018–2022; supervisor – S.V. Dzyadevich)
  8. № 17/1 - Intelligent biosensor systems for determining some metabolites to control the development of socially important human diseases (2018–2022; supervisor – O.P. Soldatkin)
  9. № 21/2 - High-performance SPR spectrometer with a sensor chip in a microarray (microarray) format. Development of the device and software (2018–2022; supervisor – O.P. Soldatkin)
  10. № 23 - Development, optimization and testing of epidermal printed amperometric sensor systems for non-invasive detection of L-lactate (2018–2022; supervisor – Ya.I. Korpan)
  11. № 25/2 - Development and preparation for serial production of wireless networks of “smart” multisensors and biosensor devices for express diagnostics of the state of grape and fruit crops and control of the wine production process (2018–2022; supervisor – L.V. Shkotova)
  12. № 26/2 - Optoelectronic smart sensor with electrochemical functions (2018–2022; supervisor – V.M. Pyeshkova)
  13. № 28/2 - Affinity sensor system based on “smart” hybrid nanocomplexes for determining specific nucleic acid sequences (2018–2022; supervisor – S.V. Dzyadevych)

Comprehensive scientific and technical program “Sensor devices for medical, environmental and industrial technological needs: metrological support and experimental operation”

  1. No. 3/1 – Development and experimental operation of a portable device based on enzyme potentiometric biosensors for the analysis of alkaloids and other natural toxins in agricultural crops and products. Creation and optimization of the operation of the bioselective element of biosensors in the device (2013-2017; supervisor – Yel`ska G.V.);
  2. No. 5/1 – Development and experimental operation of a portable analyzer based on amperometric enzymatic biosensors for quality control of beverages in winemaking. Adaptation of the operation of a portable amperometric analyzer to real operating conditions (2013-2017; supervisor – Dzyadevych S.V.);
  3. No. 8/1 – Development of electrochemical mono- and multi-sensors for the determination of the main blood metabolites: metrological support and experimental operation. Development of mono- and multi-biosensor elements. Metrology and standardization of biosensors, experimental operation (2013-2017; supervisor - Soldatkin O.P.);
  4. No. 19/1 - Development and metrological support of sensor systems for the determination of phenols based on biomimetic polymers with catalytic and receptor properties. Development of portable sensor devices for the determination of phenols (2013-2017; supervisor - Sergeyeva T.A.);
  5. No. 4/2 - Development, experimental testing and metrological certification of an enzyme multibiosensor for determining the general toxicity of solutions. Development of methods for the determination of toxic substances (2013-2017; supervisor - Soldatkin O.O.);
  6. No. 6/2 - Development of bio/chemosensor analyzers for determining the content of formaldehyde, L- and D-lactate, their metrological evaluation and experimental testing. Development, metrological support and testing of a formaldehyde analyzer based on a portable conductometer "МХР-3" and research into the possibility of its adaptation for the determination of L- and D-lactate (2013-2017; supervisor - Korpan Ya.I.);
  7. No. 7/2 - Development and experimental operation of a portable conductometric biosensor saccharide analyzer for the food industry. Optimization of the operation of the saccharide analyzer and its adaptation for use in the food industry (2013-2017; supervisor - Dzyadevych S.V.);
  8. No. 20/2 - Development, experimental testing and metrological certification of a sensor device based on the effect of localized surface plasmon resonance in arrays of gold and silver nanostructures. Experimental operation and metrological support (2013-2017; supervisor - Rachkov O.E.);

Comprehensive scientific and technical program of the NAS of Ukraine “Sensor systems for medical, ecological and industrial and technological needs”

  1. No. 3/1 – Portable analyzer of alkaloids in agricultural crops and products based on an electrochemical biosensor. Creation of a bioselective element and adaptation of its operation as part of the analyzer (2010-2012; supervisor – Yelska G.V.);
  2. No. 5/1 – Portable analyzer based on amperometric enzyme biosensors for quality control of beverages in winemaking. Development of amperometric enzyme biosensors for the determination of glucose, lactate and glycerol (2010-2012; supervisor – Dzyadevych S.V.);
  3. No. 8/1 – Multisensor based on ISPT for the determination of main blood metabolites. Development and creation of biosensor elements for the determination of glucose, urea and creatinine and study of their operation (2010-2012; supervisor – Soldatkin O.P.);
  4. No. 21/1 – Development and research of sensor systems for the determination of phenols based on biomimetic polymers with catalytic properties. Development of portable sensor systems for the determination of phenols (2010-2012; supervisor – Sergeyeva T.A.);
  5. No. 4/2 – Multibiosensor for determining the general toxicity of solutions and individual toxic substances. Development of a method for immobilizing enzymes and studying their simultaneous operation as part of a multisensor (2010-2012; supervisor – Arkhypova V.M.);
  6. No. 6/2 – Development and production of experimental samples of electrochemical biosensors for the analysis of formaldehyde in food products, pharmaceuticals and the environment. Development of a formaldehyde analyzer based on conductometric thin-film planar electrodes (2010-2012; supervisor – Korpan Ya.I.);
  7. No. 7/2 – Conductometric biosensor system for saccharide analysis in the food industry. Development of a method for immobilizing enzyme and multienzyme complexes and studying their operation (2010-2012; supervisor – Dzyadevych S.V.);
  8. No. 28/2 – Sensor based on the effect of localized surface plasmon resonance in arrays of gold nanostructures for the study of biomolecular processes, molecular spectroscopy of organic compounds and precision measurement of the refractive index. Study of biomolecular processes using a sensor based on the effect of localized surface plasmon resonance (2010-2012; supervisor – Rachkov O.E.);

State Targeted Scientific and Technical Program "Nanotechnologies and Nanomaterials"

  1. No. 24 - Optical sensor systems based on nanostructured molecularly imprinted polymer membranes for environmental monitoring and medical diagnostics (2010-2014;supervisor - Sergeyeva T.A.)
  2. No. 25 - Development of bioselective membranes based on carbon nanomaterials functionalized with biomolecules for the creation of new generation analytical microdevices (2010-2014; supervisors - Biloivan O.A. and Korpan Ya.I.)
  3. No. 5.34 - Creation and research of new nanobiomaterials based on recombinant immunoreagents and nanostructured films for nanobiosensor immunodiagnostics (2010-2014; supervisor - Soldatkin O.P.)

State Targeted Comprehensive Program of Fundamental Research "Fundamental Problems of Nanostructured Systems, Nanomaterials, Nanotechnologies" (2010-2014)

  1. No. 99-N – Research on the interaction of nucleic acids with nanocrystalline semiconductors for the creation of new bionanostructured materials capable of recognizing biologically important markers of hereditary diseases (2010-2014; supervisor – Soldatkin O.P.)

State Targeted Scientific and Technical Program for the Development and Creation of Sensory High-Intensity Products for 2008-2017

  1. No. 1.3.2 – Development and Creation of Multiparametric Devices for Express Detection and Monitoring of Chemical and Biological Liquid Compounds. Development of Methods for Immobilization of Enzymes on the Surface of Multiconverters (2010-2014; supervisor – Dzyadevych S.V.)

Grant of the NAS of Ukraine to research laboratories/groups of young scientists of the NAS of Ukraine for conducting research in priority areas of development of science and technology:

  1. 2020-2021 - No. 25/02 “Development of arginine-selective sensors for the analysis of products and dietary supplements used in preventive and rehabilitation medicine”. Supervisor - Sayapina O.Ya.
  2. 2022-2023 – No. 27/02 “Development of a biosensor system for monitoring ALT and AST in patients with liver and heart diseases”. Supervisor – Soldatkin O.O.
  3. 2024-2025 – No. 33/02 “Development of new hybridization DNA sensors modified with nanomaterials based on surface plasmon resonance”. Supervisor – Kucherenko I.S.

Current international projects:

EC Framework Programmes:

Fifth Framework Programme (FP5)

  1. EC Project 31958 INION II: "Totally integrated microengineered ion sensors for large-scale applications" (1998-2001);
  2. EC Project G5RD-CT-2002-00752 MATINOES: "Novel organic-inorganic materials in opto-electronic systems for the monitoring and control of bio-processes" (2002-2006).

Seventh Framework Programme:

  1. No 318053 - SMARTCANCERSENS: "Micro/nanosensors for early cancer warning system - diagnostic and prognostic information", (2013-2016, Project Co-Director - Yaroslav I. Korpan);
  2. No 230802 - NANOSENS: “Nanosensors and Nanomaterials”; (2009-2011, Project Co-Director - Sergey V. Dzyadevych);
  3. No 318524 - NANODEV: "Integrated nanodevices"; (2012-2015, Project Co-Director - Sergey V. Dzyadevych).

Horizon 2020 (FP8)

  1. Horizon 2020 Project # 951887 “BioNanoSens “Deeping collaboration on novel biomolecular electronics based on “smart” nanomaterials” (2020-2024; supevisor and project coordinator – S.V. Dzyadevych)
  2. Horizon 2020 Project #958491 «Waste2Fresh “Smart innovative system for recycling wastewater and creating closed loops in textile manufacturing industrial processes”» (2020-2024; supervisor and project coordinator – V.M. Pyeshkova)

Horizon Europe:

  1. №101215656 Horizon Europe Project «Research Infrastructures for the Future of Ukraine: Roadmap for Sustained Growth and Recovery» (2025-2028; supervisor and project coordinator – S.V. Dzyadevych)

СRDF:

    № 65495a «Highly selective recognition of aflatoxins in grains and feed using nanostructured of polymer membranes" (2020-2021; supervisor and project coordinator - T.A. Sergeyeva)

NATO Scientific Programmes:

  1. № CBP.NUKR.SFPP 984173 "Science for Peace" - "New electrochemical nanosensors for determination of toxic ions" (2012-2015, Manager and Principal Investigator - Yaroslav I. Korpan)
  2. № CBP.NUKR.CLG 984221 - "Development of biosensors for determination of botulinum neurotoxin and their adaptability to products examination against biological terrorist attacks" (2011-2012, Manager and Principal Investigator - Sergey V. Dzyadevych)
  3. NATO Linkage Grant 979775 (2003-2005, Manager and Principal Investigator - Sergey V. Dzyadevych)
  4. NATO Linkage Grant № LST.CLG 980008
  5. NATO Linkage Grant № LST.CLG 982788
  6. NATO Linkage Grant № LST.CLG.977342 (2000-2002, Co-Director Yaroslav I. Korpan)
  7. NATO Linkage grant № ENVIR.LG 950913 (1997)
  8. NATO Linkage Grant № ENVIR.LG 972305 (1998-2000)
  9. NATO Linkage Grant № LST.NUKR.CLG 980621 (2004-2006)
  10. NATO Linkage Grant № CBP.NUKR.CLG 982955 (2007-2009)
  11. NATO "Science for Peace" Grant № CBP.NUKR.SFP 983063 (Director - Yaroslav I. Korpan).

STCU-NASU (Science and Technology Center in Ukraine - NAS of Ukraine) projects:

  1. 2015-2017 STCU-NASU Project 5044 “Elaboration of “smart nanocarriers” based on the effect of photothermal plasmon amplification for drug target delivery in the human body”. Project Director: Sergey V. Dzyadevych
  2. 2016-2018 STCU-NASU project 6177 “Application of functional nanomaterials for creation of biosensor conductometric devices for arginine detection”. Project Director: Sergey V. Dzyadevych
  3. 2017-2018 STCU-NASU project: “Calixarene Based Chemosensors” Development of electrochemical chemosensor for determination of arginine. Project Director: Sergey V. Dzyadevych
  4. 2015-2016 STCU-NASU Project: Enzyme multibiosensor system for renal dysfunction diagnosis and hemodialysis control. Ukrainian Project Director: O. P. Soldatkin
  5. 2015-2016 STCU-NASU Project: Elaboration of "smart nanocarriers" based on the effect of photothermal plasmon amplification for drug target delivery in the human body. Ukrainian Project Director: S. V. Dzyadevych, V. I. Chegel
  6. 2016-2017 STCU-NASU Project "Nanotechnologies for application in health care, creation of new materials and devices" Project: Application of functional nanomaterials for creation of biosensor conductometric devices for arginine detection. Ukrainian Project Director: S. V. Dzyadevych, Cherenok S.

Other projects:

  1. BLACK SEA HORIZON (2016-2017) Project: Grant facilitating the participation of Black Sea countries in European Brokerage events. Ukrainian Project Director: S. V. Dzyadevych
  2. EUREKA (2014-2016) Project: Multiple biosensor device for monitoring of hemodialysis patients (HemoSensor) Ukrainian Project Director: O. P. Soldatkin
  3. French-ukrainian project Dnipro 05061 WC, 2002-2003. Project Director - Sergey V. Dzyadevych
  4. ECO-NET № 12675SG
  5. INTAS-FOOD 00-151 (2001-2003)
  6. INTAS Grant No 96-1971 (1999)
  7. INTAS Grant No 03-51-6278.

Ukrainian-Swiss Joint Project Proposal

  1. 2024-2027 – project “Novel Portable Non-Invasive Real-Time Monitoring System for Biomarker Detection in Preterm Infants 2024-2027” within the framework of the “Ukrainian-Swiss Joint Project Proposal”. Supervisor – S.V. Dzyadevych.